Roux (Imbert & Roux)
Edmond Roux and Henri Imbert registered the design for l'auto-roue Roux (The Roux Motor Wheel) in 1900, with an an addition in 1903. It is discussed in an article in "La Vie Automobile" of 1904, and it appears only one was built, powered by a single-cylinder four-stroke De Dion-Bouton engine mounted integral with the front wheel. The design had a number of flaws.
Source: Period literature.